Distinguished Visiting Professor (DVP) Lecture Series

Distinguished Visiting Professors: 2017 & 2018

September 14, 2018 Michael J. Ackerman, MD Professor of Medicine, Pediatrics and Pharmacology, Mayo Clinic “Secondary Prevention—A Missed Opportunity To Save Lives” February 26, 2018 Raymond J. Gibbons, MD Arthur M. and Gladys D. Gray Professor of Medicine, Mayo Clinic “Seeing in the Dark: Planning Interventions for Peripheral Arterial Disease” January 22, 2018 Andrew Dueck, MD Vascular Surgeon and Associate Scientist, Sunnybrook Research Institute “Seeing in the Dark: Planning Interventions for Peripheral Arterial Disease” December 1, 2017 David Taggart, MD Professor of Cardiovascular Surgery, University of Oxford “The use of randomized cardiovascular surgical trials to DISTORT best clinical practice” October 16, 2017 Mikhail Kosiborod, MD Professor of Medicine, University of Missouri-Kansas City School of Medicine “Current State of Evidence for CV Protection Via Glucose Lowering: SGLT2 Inhibition” June 29, 2017 Slava Epelman, MD Assistant Professor of Medicine, University of Toronto "Primitive Cardiac Macrophages: Role in Tissue Injury, Repair and Regeneration" June 29, 2017 Phyllis Billia, MD Assistant Professor, University of Toronto "Tumor Suppressors in Cardiac Regeneration" May 9, 2017 Allan Jaffe, MD Professor of Cardiology and Laboratory Medicine & Pathology, Mayo Clinic "In Search of Specificity – A Biomarker Odyssey" April 10, 2017 Matthew Roe, MD Professor of Medicine, Duke University "Charting the Path Forward for Pragmatic Trials for Cardiovascular Disease" March 20, 2017 Matthias G. Friedrich, MD Professor of Medicine at McGill University and Heidelberg University "Game Changing Advances in Cardiac MRI"

Distinguished Visiting Professors: 2016

February 17, 2016 Calum MacRae, MD, PhD Chief of Cardiovascular Medicine, Brigham and Women’s Hospital; Harvard Medical School "Bridging the gaps in the precision medicine paradigm" April 6, 2016 Thomas Marwick, MD Director of Baker IDI Heart and Diabetes Institute Former Director of the Menzies Research Institute at the University of Tasmania "The A to B of Heart Failure" May 30, 2016 VM Christoffels, MD Professor of Developmental Biology, University of Amsterdam "Transcriptional Regulation of Cardiac Electrical Patterning" September 6, 2016 W. H. Wilson Tang, MD Professor of Medicine, Cleveland Clinic Lerner College of Medicine at CWRU "Cardio-Renal Syndrome: Past, Present, and Future" October 17, 2016 David Brieger, MD Professor of Cardiology, University of Sydney "Risk Aversion in Cardiology Practice: Insights from Clinical Quality Registries" November 7, 2016 Chris Gale, MD Associate Professor of Cardiovascular Health Sciences, University of Leeds "Higher Resolution Insights into Acute Myocardial Infarction Care and Outcomes: #datasavelives" December 9, 2016 Osama Hamdy, MD Assistant Professor of Medicine at Harvard Medical School "Long-term Lifestyle Intervention and Cardiovascular Risk Factors: What We Know"

Distinguished Visiting Professors: 2015

Joseph Hill, MD, PhD., Professor of Internal Medicine and Molecular Biology and Chief, Division of Cardiology at the University of Texas Southwestern Medical Center "Cardioprotection: Tale of Two Mechanisms" January 26, 2015 Jacques Genest, M.D., Professor, Faculty of Medicine; Novartis Chair in Medicine, McGill University "Systems and Molecular Approaches to Severe Hyperlipidemias (SMASH)" March 2, 2015 Garret FitzGerald, M.D., McNeil Professor in Translational Medicine and Therapeutics at the University of Pennsylvania, Chair of the Department of Pharmacology and Director of the Institute for Translational Medicine and Therapeutics “Adventures with Peripheral Clocks” March 26, 2015 Eduardo Marbán, MD, PhD, Director, Cedars-Sinai Heart Institute "Therapeutic Regeneration of the “Irreversibly” Injured Human Heart" May 11, 2015 André La Gerche, MBBS, PhD, Head of Sports Cardiology at the Baker IDI Heart and Diabetes Institute Melbourne "Identifying (the few) Endurance Athletes at Risk of Arrhythmias" May 19, 2015 Robin Choudhury, MA, DM, Professor of Cardiovascular Medicine, Clinical Director Oxford Acute Vascular Imaging Centre Radcliffe Department of Medicine, University of Oxford "Characterisation of the Monocyte Response in Acute Myocardial Infarction – Insights from Transcriptomic Studies in Mice and Men" September 21, 2015 Darren McGuire, MD, MHSc, Professor of Medicine; Dallas Heart Ball Chair for Research on Heart Disease in Women "Cardiovascular Assessment of Diabetes Drugs: Selected Lessons Learned Thus Far" October 19, 2015 Peter Backx, MD, Professor, Departments of Physiology and Medicine, University of Toronto; Director, Transgenic Physiology Laboratory "Links Between Endurance Exercise and Atrial Fibrillation: What Every Sports Buff Should Know" December 7, 2015

Distinguished visiting professors 2014

Joao Lima, MD Professor of Medicine and Radiology, Director of Cardiovascular Imaging at Johns Hopkins Hospital Title: Myocardial Fibrosis in Incident Heart Failure in the US: Lessons from MESA January 13, 2014 Justin Ezekowitz, MD Associate Professor of Medicine in the Division of Cardiology at the University of Alberta Title: Acute Heart Failure: Risk and Endpoints January 27, 2014 Deepak Bhatt, MD, MPH Professor of Medicine at Harvard Medical School Title: Advances in Antiplatelet Therapy February 20, 2014 Robert Giugliano, MD Senior Investigator at TIMI Study Group; and Associate Professor of Medicine at Harvard Medical School Title: Target Specific Oral Anticoagulants for Atrial Fibrillation March 25, 2014 Euan Ashley, MD Associate Professor of Medicine (Cardiovascular), of Genetics and of Pathology at the Stanford University Medical Center Title: Six Degrees: Networks, Systems and Therapeutics in Cardiovascular Biology April 28, 2014 Stefan D. Anker, MD Professor of Innovative Clinical Trials (Cardiology & Cachexia Research) University Medical Center Göttingen (UMG), Göttingen, Germany Title: Co-morbidities in Heart Failure: Update on Cachexia & Iron Deficiency November 12, 2014 Vivek Rao, MD Chief of Cardiovascular Surgery, Munk Professor in Advanced Cardiac Therapeutics at Peter Munk Cardiac Centre, and Professor of Surgery at the University of Toronto Title: Translational Concepts in Regenerative Medicine: Pitfalls with Innovation December 1, 2014

Distinguished visiting professors 2013

Denisa Wagner, PhD Department of Pathology, Harvard Medical School Title: NETs: Linking Inflammation and Thrombosis January 14, 2013 David Hood, PhD Professor, York University Title: Molecular mechanisms of mitochondrial adaptations in aged skeletal muscle February 11, 2013 Kai C. Wollert Professor of Molecular and Translational Cardiology, Hans-Borst Center for Heart & Stem Cell Research Title: Paracrine signaling in the heart: novel players and emerging clinical applications March 4, 2013 Pieter de Tombe, PhD James R. DePauw Professor of Cell and Molecular Physiology, Co-Director, Cardiovascular Research Institute, Loyola University Title: Myocardial Sarcomere Dynamics in Health and Disease April 3, 2013 Paul Armstrong, MD Professor of Medicine, University of Alberta Title: Lessons Learned and Roads Untraveled; Perspectives of a Clinical Investigator April 29, 2013 Keith A Fox, MD Professor of Medicine, University of Edinburgh Title: Acute Coronary Syndrome: Have we reached the limits? May 6, 2013 Arie Horowitz, D.Sc. Assistant Professor, Department of Molecular Cardiology Lerner Research Institute, Cleveland Clinic Foundation Title: Exploiting membrane traffic for targeting angiogenesis June 10, 2013 Duncan Stewart, MD CEO and Scientific Director of the Ottawa Hospital Research Institute, Vice-President of Research at the Ottawa Hospital and Professor of Medicine at the University of Ottawa Title: Cell therapies for cardiovascular disease – version 2.0 September 30, 2013 Naveen Pereira, MD Assistant Professor of Medicine; Division of Cardiovascular Diseases, Mayo Clinic Title: Clopidogrel Pharmacogenetics: Can We Impact Clinical Practice? October 15, 2013 David Alan Kass, MD Director of the Johns Hopkins Center for Molecular Cardiovascular Biology and Professor of Medicine, Biomedical Engineering and Cellular and Molecular Medicine, John Hopkins University Title: Reverse Engineering Cardiac Resynchronization November 4, 2013 Mansoor Husain, MD Director of the Toronto General Research Institute, Professor of Medicine, Physiology, and Laboratory Medicine and Pathiobiology and former Director of the Heart & Stroke/Richard Lewar Centre of Excellence. Title: Molecular studies of cardiovascular disease: Toronto-style December 16, 2013

Distinguished visiting professors 2012

Toren Finkel, MD, PhD Chief, Center for Molecular Medicine, National Heart, Lung, and Blood Institute NIH Adjunct Associate Professor of Medicine, Johns Hopkins School of Medicine Title: How understanding the mechanisms of aging can lead to new therapies for cardiovascular disease January 23, 2012 Mikhail Kosiborod, MD, FACC, FAHA Training Program Director, American Heart Association Outcomes Research Postdoctoral Fellowship, Mid America Heart Institute of Saint-Luke’s Hospital, Kansas City Clinical Scholar, Mid America Heart Institute/Saint Luke’s Hospital, Kansas City Associate Professor, University of Missouri - Kansas City School of Medicine, Kansas City Title: Blood Glucose in Acute MI: Trials, Tribulations and Future Directions February 13, 2012 John S. Ikonomidis, MD, PhD, FRCS(C), FACS, FAHA, FACC Horace G. Smithy Professor, Chief, Division of Cardiothoracic Surgery Director, South Carolina Heart Valve Center Director, Heart and Vascular Service Line Medical University of South Carolina Title: Proteinase Systems and Thoracic Aortic Aneurysm Progression March 26, 2012 Jeff Robbins, PhD, FAHA Professor, Department of Pediatrics & Director, Division of Molecular Cardiovascular Biology, Associate Chair, Children’s Hospital Research Foundation Executive Co-Director, The Heart Institute, Cincinnati Children’s Hospital Medical Center Title: Proteotoxicity and Cardiac Disease April 30, 2012 Philippe Menasche, MD, PhD Professor of Thoracic and Cardiovascular Surgery, University Paris Descartes, Director, Heart Failure Surgical Unit, Hôpital Européan George Pompidou, Paris Title: Pluripotent stem cell engraftment to enhance ventricular function June 25, 2012 Ronald Li, PhD Director, Stem Cell and Regenerative Medicine Consortium, Li Ka Shing Faculty of Medicine, University of Hong Kong, Professor of Medicine and Physiology, University of Hong Kong Title: Cell- and Gene-based Approaches for Engineering Bio-artificial Human Heart Cells and Tissues: How close are we? October 1, 2012 William McKenna, MD Professor of Cardiology, Institute of Cardiovascular Science, University College London, Director Inherited Cardiovascular Disease, The Heart Hospital Title: Arrhythmogenesis in Desmosomal Disease October 15, 2012

Distinguished visiting professors 2011

Jean-Claude Tardif, MD Director, MHI Research Center Professor of Medicine, Université de Montréal Endowed Research Chair in Atherosclerosis Montreal Heart Institute, Université de Montréal Title: Pivotal Role of Heart Rate in Atherosclerosis January 24, 2011 Rob Beanlands, MD Chief, Cardiac Imaging Director, Cardiac PET Centre Professor of Medicine (Cardiology)/Radiology (Cross-Appointment) Division of Cardiology - University of Ottawa Heart Institute Title: Imaging in Heart Failure: The Big Picture April 18, 2011 Randy Seeley, PhD Donald C. Harrison Endowed Chair, Professor, Director of the Cincinnati Diabetes and Obesity Center, Director of the Obesity Research Center. University of Cincinnati. Title: How obesity goes to our heads: Unique aspects of CNS regulation of food intake and body weight May 09, 2011 Thomas Force, MD James C. Wilson Professor of Medicine, Thomas Jefferson University, Philadelphia Clinical Director, Center for Translational Medicine, Jefferson Medical College Title: Protein Kinases in the Heart: Targets old and new regulating injury and repair September 26, 2011

Distinguished visiting professors 2010

Aly Karsan, MD, BC Cancer Research Centre, Vancouver, Canada Senior Scientist, Medical Biophysics, BC Cancer Agency. Professor of Pathology, University of British Columbia. Health Research Scholar - Michael Smith Foundation for Health Research. CIHR Clinician-Scientist (1993-2003). Title: The Role of Notch in Mesenchymal Transformation January 18, 2010 Jason Dyck, PhD, Edmonton, Alberta Professor and Director Cardiovascular Research Centre Canada Research Chair in Molecular Biology of Heart Disease and Metabolism AHFMR Senior Scholar, Department of Pediatrics, University of Alberta Title: Molecular signalling pathways involved in the regulation of cardiac hypertrophy February 1, 2010 Derek Yellon, University College London Hospital & Medical School Director of the Hatter Cardiovascular Institute & Head of the Research Department of Cardiovascular Medicine Title: Protecting the heart from ischaemia/reperfusion injury: from laboratory bench to hospital bedside March 1, 2010 Geoff Pickering, MD, PhD London, Ontario Professor, Departments of Medicine, Biochemistry, and Medical Biophysics Robart Research, University of Western Ontario Title: Stabilizing the vulnerable vasculature April 12 2010 Martin Bennett, PhD Cambridge, UK BHF Professor of Cardiovascular Sciences/ Honorary Consultant Cardiologist Division of Cardiovascular Medicine Addenbrooke’s Centre for Clinical Investigation, Title: The role and origin of smooth muscle cells in atherosclerosis May 3, 2010 Stefan Offermanns, PhD, Heidelberg, Germany Director, Professor of Pharmacology, Institute of Pharmacology. University of Heidelberg Title: G-protein-mediated signaling in cardiovascular physiology and pathology May 31, 2010 Hartmut Weiler, PhD Senior Investigator,Blood Research Institute, Blood Center of Wisconsin Assistant Professor, Department of Physiology, Medical College of Wisconsin Director, Transgenic Core, Medical College of Wisconsin Title: Anticoagulant responses to injury - Biology of the Thrombomodulin-protein C system October 4, 2010 Edward O’Brien, MD Professor of Medicine (Cardiology) Research Chair (Canadian Institutes of Health Research / Medtronic) University of Ottawa Heart Institute Title: Heat Shock Protein 27 - A Novel Anti-atherogenesis Factor November 1, 2010 Michael Rosen, MD New York Gustavus A. Pfeiffer Professor of Pharmacology Professor of Pediatrics Director, Center for Molecular Therapeutics Columbia University Title: Why T waves change… Exploring the links between signals and responses November 8, 2010

Distinguished visiting professors 2009

Heinrich Taegtmeyer, MD, PhD University of Texas Health Sciences Centre at Houston Title: Too Much of a Good Thing - Insulin Resistance and the Heart January 26, 2009 Don Maurice, PhD Queen’s University Title: Compartment-Specific Cellular Cyclic Nucleotide Signaling - No Longer the Last Refuge of Scoundrels March 30, 2009 Stanley Nattel, MD, University of Montreal, Montreal Heart Institute Title: Molecular Determinants of Atrial Fibrillation April 20, 2009 Todd Anderson, MD, University of Calgary Title: The Prognostic Significance of Endothelial Dysfunction May 4, 2009 Ira Goldberg, MD, Columbia University Title: Correcting Lipotoxicity May 18, 2009 Peng-Sheng Chen, MD, Indiana University School of Medicine Title: The Initiation of the Heart Beat September 21, 2009

Distinguished visiting professors 2008

Dr. Gary Lopaschuk, Scientific Director, Mazankowski Alberta Heart Institute; Professor, Department of Pediatrics and Adjunct Professor, Department of Pharmacology,Faculty of Medicine & Dentistry, University of Alberta Title: Optimizing cardiac energy metabolism as an approach to treating ischemic heart disease and heart failure January 14, 2008 Dr. Richard Schulz, Professor, Departments of Pediatrics and Pharmacology University of Alberta Title: MicroRNA Regulation of Cardiac Development and Disease April 28th, 2008 Dr. David Gutterman, Northwestern Mutual Professor of Cardiology, Senior Associate Dean for Research Medical College of Wisconsin Title: Flow-induced vasodilation in the human heart - from endothelial mechanisms to clinical implications May 26, 2008 Dr. Paul Kubes, Professor, Departments of Physiology & Biophysics and Medicine Director, Calvin, Phoebe & Joan Snyder Institute of Infection, Immunity and Inflammation University of Calgary Health Sciences Centre Title: Mechanisms of leukocyte recruitment in inflammation June 9, 2008 Dr. Donald Bers, Professor and Chairman, Department of Physiology Loyola University Chicago, Stritch School of Medicine Title: Ca and CaMKII in Heart Failure - E-C Coupling, Arrhythmogenesis & Transcriptional Regulation February 25, 2008

Distinguished visiting professors 2007

Dr. Michael Gollob, Cardiac Electrophysiologist, University of Ottawa Heart Institute Assistant Professor, Division of Cardiology, Department of Medicine, University of Ottawa Title: The Genetic Basis of Cardiac Arrhythmias February 19, 2007 Dr. William Sessa, Professor of Pharmacology, Yale University School of Medicine, Vice Chairman, Department of Pharmacology, Deputy Director, Vascular Biology & Transplantation Program Title: Novel mechanisms of angiogenesis and vascular remodeling - Insights from proteomics April 16, 2007 Dr. Daniel P. Kelly, Professor of Medicine and Molecular Biology & Pharmacology Center for Cardiovascular Research Washington University School of Medicine St. Louis, MO Title: Nuclear receptor signaling in the normal and failing heart May 3, 2007 Dr. Avril V. Somlyo, Professor of Molecular Physiology and Biological Physics, Professor of Pathology, University of Virginia School of Medicine, Charlottesville Title: Signaling from membranes to crossbridges in smooth muscle and a novel role for N-cadherin in conduction in the heart June 4, 2007 Dr. Bruce McManus, MD, PhD, Professor in the Department of Pathology and Laboratory Medicine, University of British Columbia, Director of the iCAPTURE Centre and Scientifc Director of the Heart Centre at Providence Health Care Title: Predictive and Diagnostic Biomarkers in Transplantation September 24, 2007 Dr. David Beech, PhD, Professor of Molecular and Cellular Physiology, Institute of Membrane & Systems Biology, Faculty of Biological Sciences, University of Leeds Title: Ion Channel Switching and Activation in Occlusive Vascular Disease October 1, 2007 Dr. Mordecai Blaustein, MD, Professor, Department of Physiology Director, Maryland Center for Heart, Hypertension and Kidney Disease Title: Salt licks and salt tricks. How salt retention causes hypertension November 12, 2007

Distinguished visiting professors 2006

Dr. Ed Yeh, MD Chair of Cardiology M.D. Anderson Cancer Center Director, Research Center for Cardiovascular Diseases University of Texas Health Science Center Houston, TX U.S.A. Title: To Mend a Broken Heart - Stem Cell for Myocardial Regeneration February 27, 2006 Dr. Charles Murry, MD, PhD Professor of Pathology Director, Centre for Cardiovascular Biology and Regenerative Medicine University of Washington Seattle, WA Title: Stem Cell Therapy for the Infarcted Heart April 03, 2006 Dr. Ron Victor, Professor and Chief, Internal Medicine -Hypertension Division Graduate School of Biomedical Science UT Southwestern Medical Center at Dallas Title: Functional Ischemia as a cause of Duchenne Muscular Dystrophy - From Bench to Bedside and Back and Forth April 24, 2006 Dr. Joseph Loscalzo, Hersey Professor of the Theory and Practice of Medicine, Harvard Medical School; Chairman, Department of Medicine; Physician-in-Chief, Brigham and Women’s Hospital Boston, Massachusetts Title: Homocysteine and Atherothrombosis - Mechanisms, Controversies, and Future Directions October 30, 2006 Dr. Lorrie A. Kirshenbaum, Professor Departments of Physiology and Pharmacology & Therapeutics, Institute of Cardiovascular Sciences, St. Boniface General Hospital Research Centre, Canada Research Chair in Molecular Cardiology Title: "Molecular Regulators of Apoptosis” - Cross Roads Where Life Meets Death November 20, 2006 Dr. Kenneth Walsh, Ph.D. Professor of Medicine Head, Molecular Cardiology Whitaker Cardiovascular Institute Boston University School of Medicine Title: Molecular Regulators of Apoptosis: Cross Roads Where Life Meets Death December 04, 2006

Distinguished visiting professors 2005

Dr. Rick Moss, Chair, Department of Physiology University of Wisconsin Madison, WI U.S.A. Title: The Paradox of Hyper-Contractility and Cardiac Insufficiency - Insights from the cMyBP-C Null Mouse November 21, 2005 Dr. Jean-Claude Tardif, MD, Associate Professor, Department of Medicine, Director, Montreal Heart Institute Research Centre, Pfizer and CIHR Chair in Atherosclerosis, Montreal, PQ Title: Regression of Atherosclerosis and of Related Clinical Events May 02, 2005 Dr. Jagut Narula, MD, PhD, Associate Dean, College of Medicine, Chief of Cardiology, and Professor of Medicine, University of California, Irvine, Irvine, CA Title: Novel Imaging of Myocardial Remodeling and Heart Failure April 18, 2005 Ralph A. Kelly, Vice President, Clinical Affairs - Genzyme Corporation, Framingham, MA Title: Targeting the Tissue Response to Hypoxia - Therapeutic Angiogenesis with a Constitutively Active HIF-1a Transgene April 04, 2005 Dr. Gordon F. Tomaselli, MD, Professor of Medicine, Division of Cardiology & Molecular Medicine; Vice-Chair of Research, Department of Medicine, Johns Hopkins University, Baltimore, MD Title: Electrical Remodeling in the Failing Heart - Implications for Sudden Cardiac Death February 28, 2005 Dr. Evangelos Michelakis, Associate Professor of Medicine & Director of the Pulmonary Hypertension Program, University of Alberta. Title: Mitochondria at the Crossroads of Vascular Disease and Cancer - Novel Therapeutic Approaches January 31, 2005 Dr. Steven R. Houser, PhD, Laura H. Carnell Professor of Physiology. Director, Cardiovascular Research Center, Temple University School of Medicine, Philadelphia, PA Title: Mechanisms for Depressed Contractility in Heart Failure - How Can We Fix Them? January 17, 2005

Distinguished visiting professors 2004

Dr. Murray W. Huff, PhD, Professor, Department of Medicine & Endocrinology, Director, Vascular Biology Group, Robarts Research Institute, University of Western Ontario, London, Ontario Title: Novel targets for the regulation of hepatic cholesterol homeostasis - Impact on the kinetics of apoB100 metabolism in vivo November 22, 2004 Dr. Alvin H. Schmaier, MD, Professor of Internal Medicine & Pathology, Director, Coagulation Laboratory, University of Michigan, Ann Arbor, MI Title: Linking Blood Pressure Control with Thrombosis; A Novel Interaction Between the Plasma Kallikrein/Kinin and Renin Angiotensin Systems October 18, 2004 Dr. Eric Peterson, Associate Professor of Medicine, Director of CV Outcomes Research & Quality, Duke University Medical Center, Durham, NC Title: CQI in Cardiac Care - Ending Business as Usual May 31, 2004 Dr. Robert Califf, Professor of Medicine, Associate Vice Chancellor for Clinical Research, Director, Duke Clinical Research Institute, Durham, NC Title: The Heart Failure Quartet - 4 Large Trials in Heart Failure Populations April 26, 2004 Dr. Jeffery D. Molkentin, PhD, Associate Professor, Children's Hospital Medical Center, Molecular Cardiovascular Biology, Cincinnati, OH Title: PKCalpha - A Novel Regulator of Cardiac Contractility and Heart Failure April 05, 2004 Dr. E. Dale Abel, MD, PhD, Assistant Professor of Medicine & Biochemistry, Division of Endocrinology, Diabetes and Metabolism, University of Utah, School of Medicine, Salt Lake City, Utah Title: Myocardial Insulin Resistance and Cardiac Dysfunction in Obesity and Diabetes February 09, 2004 Dr. Stephen L. Archer, Professor of Medicine & Physiology, Director, Division of Cardiology, Heart & Stroke Chair in Cardiovascular Research, University of Alberta, Edmonton, AB Title: Everything You Wanted To Know About Potassium Channels; But We’re Afraid To Ask January 12, 2004

Distinguished visiting professors 2003

Dr. Karl T. Weber, MD, Neuton Stern Professor of Cardiovascular Medicine, Director, Division of Cardiovascular Diseases, University of Tennessee Health Sciences Center, Memphis, Tennessee Title: Aldosteronism - A New Perspective on the Neuroendocrine-Immune Interface November 03, 2003 Dr. Richard Theodore Lee, Associate Professor of Medicine, Harvard Medical School, Cambridge, MA Title: Liquid Heart: Injectable Microenvironments for Cardiac Regeneration October 20, 2003 Dr. Michael Schneider, Professor, Centre for Cardiovascular Development, Baylor College of Medicine, Houston, TX Title: Cardiac progenitor cells from adult myocardium - Homing, differentiation, and fusion following infarction September 29, 2003 Dr. Peter Paré, Professor, Department of Medicine, University of British Columbia, Vancouver, B.C. Title: Finding susceptibility Genes for Complex Genetic Pulmonary and Cardiovascular Disease March 24, 2003 Dr. Kenneth Chien, Professor, University of California at San Diego Department of Medicine and the Salk Institute, San Diego, CA Title: Genotype, Phenotype: Upstairs, downstairs in the family of cardiomyopathies March 03, 2003 Dr. Scott Heximer, Assistant Professor, Department of Physiology and Heart & Stroke/Richard Lewar Centre of Excellence, University of Toronto, Toronto Title: Hypertension and Prolonged Vasoconstrictor Signaling in RGS-2 Deficient Mice January 27, 2003

Distinguished visiting professors 2002

Dr. Josef Penninger, Staff Scientist Amgen Institute Ontario Cancer Institute/Princess Margaret Hospital, Associate Professor, Departments of Immunology and Medical Biophysics University of Toronto, Associate Professor, Department of Experimental Pathology University of Innsbruck, Austria. Title: Control of Heart Size and Heart Function by P13K Signaling November 04, 2002 Dr. Joshua M. Hare, MD, Associate Professor of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD Title: The use of stem cells in the repair of myocardial infarction September 30, 2002 Dr. Marlene Rabinovitch, M.D., F.R.C.P.(C)., F.A.C.C., HSFO Endowed Research Chair, Professor of Pediatrics, Medicine, Laboratory Medicine & Pathobiology, University of Toronto, Director, Cardiovascular Research Program, The Hospital for Sick Children Title: The Ductus Arteriosus and Gene Regulation June 17, 2002 Dr. Janet Rossant, Professor of Molecular & Medical Genetics and Obstetrics & Gynecology, University of Toronto, Joint Head, Program in Development and Fetal Health,Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario Title: Mouse Mutagenesis – Models of Human Disease April 22, 2002 Dr. Mark L. Entman, Professor of Medicine and Biochemistry, Chief, Cardiovascular Sciences Section, Department of Medicine, Scientific Director, The DeBakey Heart Center, Baylor College of Medicine, Houston, Texas Title: Inflammation in Cardiac Protection and Repair March 25, 2002

Distinguished visiting professors 2001

Dr. Carlos M. Ferrario, Professor of Physiology and Pharmacology, Director, The Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, North Carolina Title: The Renin Antiotensin System - A Link to the Pathogenesis of Atherosclerosis November 26, 2001 Dr. Simon Pimstone, MD, PhD, FRCPC, Founder and Vice President, Clinical and Medical Affairs, Xenon Genetics Inc. Title: Treating Common Human Disease - Insights from Rare Genetic Disorders October 29, 2001 Dr. Jennifer E. Van Eyk, Assistant Professor, Department of Physiology, Queen's University Title: Proteomics: In Search for the Proteins that Cause Heart Disease September 24, 2001 Dr. Mark W. Majesky, Associate Professor, Department of Pathology, Center for Cardiovascular Development Baylor College of Medicine, Texas A&M University, Houston, Texas Title: Molecular Pathways Controlling Coronary Smooth Muscle Differentiation from Proepicardial Cells April 23, 2001 Dr. Thomas N. Wight, Affiliate Professor of Pathology, University of Washington, and Chair, Vascular Biology, Hope Heart Institute, Seattle, Washington Title: Proteoglycans and Hyaluronan are Extracellular Matrix Molecules that Regulate Key Events in Atherosclerosis and Restenosis. March 26, 2001 Dr. Joseph Metzger, PhD, Associate Professor of Physiology and Internal Medicine, The University of Michigan Medical School Title: Genetic Engineering in the Heart by Transgenesis and DNA-Virus Gene Transfer February 12, 2001

Distinguished visiting professors 2000

Dr. Pavel Hamet, Professor,. Departments of Medicine, Physiology and Nutrition, University of Montreal; Director of Research, Research centre of the Centre Hospitalier de l'Universite de Montreal (CHUM). Title: Chasing the Genes of Hypertension November 20, 2000 Dr. Barbara J. Deal, Professor of Pediatrics Northwestern University Medical School, Clinical Associate Professor of Pediatrics, University of Wisconsin Children's Hospital. Title: Novel Approaches to the Management of Arrhythmias in Complex Congenital Disease in the Adult October 16, 2000 Dr. Robert Hegele, Professor of Medicine and Biochemistry, Robarts Research Institute, University of Western Ontario. Title: Genetic Studies of Atherosclerosis in Canadian Sub-Populations September 18, 2000 Dr. Jonathan Epstein, Assistant Professor of Medicine, Hospital of the University of Pennsylvania Title: Role of Pax3 in Muscle and Cardiac Development June 28, 2000 Dr. Paul Kubes, Professor, Departments of Physiology, Biophysics and Medicine, University of Calgary Health Sciences Centre Title: The Cardiovascular System and the Inflammatory Response - Use of Knockout Mice May 15, 2000 Dr. David A. Dichek, Associate Investigator of the Gladstone Institute of Cardiovascular Disease, Associate Professor of Medicine, UCSF Title: Vascular Gene Transfer - New Biology and New Technology May 1, 2000 Dr. Bjorne Dahlof, Associate Professor of Medicine, Director Clinical Trial Unit, Sahlgrenski University Hospital/Ostra Goteborg University Title: Importance of Treating Hypertension - Current and Future Treatment Options April 18, 2000 Dr. Salim Yusuf, Professor of Medicine, Head Division of Cardiology, McMaster University Title: The Global Burden of Cardiovascular Disease April 17, 2000 Dr. Michael Zile, Professor of Medicine, Medical University of South Carolina Heart Centre Title: Diastolic Heart Failure - Cellular and Extracellular Mechanisms April 10, 2000 Dr. Randy Chitwood , Cardiothoracic Surgeon, Brody School of Medicine, East Carolina University Title: Videoscopic and Robotic Mitral Valve Surgery at Dawn of the New Millennium February 25, 2000 Dr. John Burnett, Professor of Medicine Mayo Clinic Title: Vasopeptidase Inhibition - A New Target in Cardiovascular Disease January 14, 2000

Distinguished visiting professors 1999

Dr. Stephen Schwartz, Professor of Pathology, University of Washington Title: Origins of the Aortic Intima: Soil for Atherosclerosis December 9, 1999 Dr. Jeffery Molkentin, Assistant Professor of Pediatrics, University of Cincinnati, Children's Hospital Medical Centre Title: Intracellular Signaling Pathways that Regulate Cardiac Hypertrophy - Role of Calcineruin/NFAT3 October 28, 1999 Dr. Deepak Srivastava, Assistant Professor of Pediatrics, University of Texas Southewestern Medical Centre Title: The Molecular Basis of Cardiac Development and Congenital Heart Disease October 7, 1999 Dr. Eduardo Marban, Professor of Medicine and Physiology, Johns Hopkins University Modification of Neuronal and Cardiac Excitability by Ion Channel Title: Gene Transfer - First Step Towards Gene Therapy of Excitability Disorders September 21, 1999